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Icariin
CAS No.: 489-32-7
Product Name: Horny goat weed extract/ Epimedium extract/Epimedium P.E
Latin Name: Epimedium grandiflorum L.
Plant source: Epimedium
Specification : 5:1,10:1,20:1 or accoding to your request.
Ingredient: Icariin/Epinedoside A
Herb Source: Epimedium
Content: Icariin 5%,10%,20%,50%,70%,90%
Formula: C33H40O15
Exact Mass: 676.237
Molecular Weight: 676.662
PSA: 238.2
LogP: 0.0679
Assay Method: HPLC
Appearance: Brown or yellow fine powder
Storage: Store in cool & dry place, and keep away from strong light and heat.
Shelf Time: 2 years when properly stored
Package: 25kg/drum, inner with double-layer plastic bags
Pharmacological effects
1. The impact on sexual function
Epimedium extract has a certain role in promoting gonadal function. Flavonoids such as icariin have kidney impotence, 30 ~ 1000 μg / l can promote the secretion of estradiol in granulosa cells, at 1000 μg / l can promote adrenocortical cells to secrete corticosterone. At the same time EPS can increase the level of gonadal hormone, the main increase in the level of FSH.
2. Improve the body's immune function
Pomace epimedium 50% methanol extract can inhibit lymphocyte transformation. Epimedium flavonoids can make "Yang" mouse cell function and high antibody, significantly enhance the body's immune function of T cells. Both EPS and EI have immunomodulatory effects.
Antioxidant
EPS and EI have antioxidant activity can enhance antioxidant enzyme activity, reduce the role of free radical products.
Anti-aging effect
Epimedium extract can affect the longevity of life by affecting the passage of cells, prolonging the growth period, regulating the immune and secretion systems, improving the body metabolism and various organ functions.
5 on the cardiovascular effect
Epimedium alcohol leaching solution in the non-amino acids can significantly increase the isolated rabbit heart coronary flow. Decoction and alcohol extract blood pressure lowering effect. Icariin can directly relax vascular smooth muscle, can dilate coronary artery, femoral artery and cerebral artery. The mechanism of action is to inhibit the extracellular calcium influx in vascular smooth muscle cells.
6. other role
Prevent osteoporosis, Epimedium crude extract expectorant, antitussive and antiasthmatic effect..
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